MERCK Orbax Suspension is a malt flavored antibiotic suspension containing orbifloxacin, which is a synthetic broad-spectrum antibacterial agent from the class of fluoroquinolone carboxylic acid derivatives. Orbifloxacin is bound to a patented taste-masking agent so it passes taste buds undetected, then is released in the low pH environment of the stomach.

Dogs and Cats

• Treats skin infections (wounds and abscesses) in cats
• Treats skin and soft tissue infections (wounds and abscesses) and urinary tract infections (cystitis) in dogs

orbifloxacin

Serious side effects are not expected when used at therapeutic doses. Possible side effects may include vomiting, soft stools, reduced appetite, lethargy, itching and rashes. If these symptoms persist and appear troublesome, contact your veterinarian. Orbifloxacin and other quinolones have been shown to cause cartilage damage in immature growing animals and use should be avoided in young animals (

Other side effects may occur. If you notice anything unusual, contact your veterinarian.

Orbax Suspension should be administered as directed by your veterinarian. Before initial use, shake the suspension thoroughly. Remove the cap and insert the syringe adaptor by pressing firmly into top of bottle. Insert the syringe tip into the adaptor opening and invert the bottle. Withdraw the required amount of medication with the calibrated syringe. After use, replace cap, leaving adaptor in the bottle, and rinse the syringe with water. Give this medication to your pet for the time period prescribed by your veterinarian, even if it appears the pet is feeling better. This will help to ensure the infection is all cleared up.

Orbifloxacin and other quinolones have been shown to cause arthropathy in immature animals of most species tested. Compounds (e.g., sucralfate, antacids, and multivitamins) containing divalent and trivalent cautions (e.g., iron, aluminum, calcium, magnesium, and zinc) may substantially interfere with the absorption of quinolones resulting in a decrease in product bioavailability. The use of fluoroquinolones in cats has been reported to adversely affect the retina and should be used with caution in cats.

Make sure to tell your veterinarian what other medication you are giving your pet. The following drugs can potentially interact with quinolones: antacids, cimetidine, sucralfate, nitrofurantoin, cyclosporine, theophylline, and probenecid. Quite often your veterinarian may prescribe two different medications, and a drug interaction may be anticipated. In this case, your veterinarian may vary the dose and/or monitor your pet more closely. Contact your veterinarian if your pet experiences any unusual reactions when different medications are given together. Certain compounds (e.g., vitamins, antacids, iron) may interfere with the absorption of fluoroquinolone antibiotics. Administration of this drug with vitamin/mineral supplements and/or antacids should be avoided or discussed with your veterinarian.

Allergic reactions to medications may occur. Be sure to inform VetSource and your veterinarian if your pet has any known drug sensitivities or allergies. If your pet displays symptoms of an allergic reaction, call your veterinarian immediately or go to a veterinary emergency clinic. Symptoms may include but are not limited to: swollen lips, tongue, face, airways; difficulty breathing; agitation; profuse salivation; vomiting; widespread hives and itching.